Research by Lab

Chris ChidleyFrom systems-level mapping to functional understanding of nutrient transport in normal and cancer cells
Chris CounterMolecular mechanisms underlying the evolution of normal cells into cancer
Alicia DarnellMetabolic regulation of protein synthesis at the ribosome
Donald FoxExtreme genome variation in organ development, repair, and disease
Sarah GoetzCilia regulation in development and disease
Timothy HaysteadDiscovery and development of novel SMIs targeting purine-utilizing proteins involved in human disease
Michael KastanStress response pathways in mammalian cells
Cynthia KuhnUsing animal and model systems to study the biology of addiction and stress/depression
David MacAlpineMechanisms of genetic and epigenetic inheritance
Donald McDonnellIdentify novel therapeutics for use in the treatment and prevention of hormonally responsive cancers
Chris NewgardMechanisms of metabolic regulation and fuel homeostasis in mammalian systems
Trudy OliverInnovative approaches to combating lung cancer
Ann Marie PendergastTyrosine kinase signaling networks in cancer metastasis and the response to injury and regeneration
Theodore SlotkinEffects of endocrine status, environmental toxicants and drugs on brain development
Nina TsvetanovaBiochemical and spatial regulation of GPCR signaling networks and their impact on physiology
G. Greg WangChromatin biology, human disease and therapeutics
Xiao-Fan WangMechanisms underlying cellular senescence and tumorigenesis
Andrew WestMolecular mechanisms and genetics of neurodegeneration
Laura WinglerMechanisms of selective signaling pathway activation by GPCR ligands and drugs
Kris WoodNovel tumor vulnerabilities and systems-based strategies to overcome therapeutic resistance
Tso-Pang YaoBiology of the histone deacetylase HDAC family and the clinical utility of HDAC inhibitors
Zhao (ZZ) ZhangImpact and regulation of transposons in both reproductive and somatic tissues
Lee ZouPrinciples of cellular responses to chromosomal insults and their roles in the maintenance of genomic stability