| Chris Chidley | From systems-level mapping to functional understanding of nutrient transport in normal and cancer cells |
| Chris Counter | Molecular mechanisms underlying the evolution of normal cells into cancer |
| Alicia Darnell | Metabolic regulation of protein synthesis at the ribosome |
| Donald Fox | Extreme genome variation in organ development, repair, and disease |
| Sarah Goetz | Cilia regulation in development and disease |
| Timothy Haystead | Discovery and development of novel SMIs targeting purine-utilizing proteins involved in human disease |
| Michael Kastan | Stress response pathways in mammalian cells |
| Cynthia Kuhn | Using animal and model systems to study the biology of addiction and stress/depression |
| David MacAlpine | Mechanisms of genetic and epigenetic inheritance |
| Donald McDonnell | Identify novel therapeutics for use in the treatment and prevention of hormonally responsive cancers |
| Chris Newgard | Mechanisms of metabolic regulation and fuel homeostasis in mammalian systems |
| Trudy Oliver | Innovative approaches to combating lung cancer |
| Ann Marie Pendergast | Tyrosine kinase signaling networks in cancer metastasis and the response to injury and regeneration |
| Theodore Slotkin | Effects of endocrine status, environmental toxicants and drugs on brain development |
| Nina Tsvetanova | Biochemical and spatial regulation of GPCR signaling networks and their impact on physiology |
| Antonius VanDongen | The role of the immediate-early gene Arc in the pathophysiology of Alzheimer’s disease |
| G. Greg Wang | Chromatin biology, human disease and therapeutics |
| Xiao-Fan Wang | Mechanisms underlying cellular senescence and tumorigenesis |
| Andrew West | Molecular mechanisms and genetics of neurodegeneration |
| Laura Wingler | Mechanisms of selective signaling pathway activation by GPCR ligands and drugs |
| Kris Wood | Novel tumor vulnerabilities and systems-based strategies to overcome therapeutic resistance |
| Tso-Pang Yao | Biology of the histone deacetylase HDAC family and the clinical utility of HDAC inhibitors |
| Zhao (ZZ) Zhang | Impact and regulation of transposons in both reproductive and somatic tissues |
| Lee Zou | Principles of cellular responses to chromosomal insults and their roles in the maintenance of genomic stability |